• Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation 

      Gerogianni, Alexandra; Dimitrov, Jordan D.; Zarantonello, Alessandra; Poillerat, Victoria; Chonat, Satheesh; Sandholm, Kerstin; McAdam, Karin E.; Ekdahl, Kristina N.; Mollnes, Tom Eirik; Mohlin, Camilla; Roumenina, Lubka T.; Nilsson, Per (Peer reviewed; Journal article, 2022)
      Hemolysis, as a result of disease or exposure to biomaterials, is characterized by excess amounts of cell-free heme intravascularly and consumption of the protective heme-scavenger proteins in plasma. The liberation of ...